Insulin glulisine is a rapid-acting insulin analog that differs from human insulin in that the amino acid asparagine at position B3 is replaced by lysine and the lysine in position B29 is replaced by glutamic acid. It was developed by Sanofi-Aventis and is sold under the trade name Apidra. When injected subcutaneously, it appears in the blood earlier than human insulin. When used as a mealtime insulin, the dose is to be administered within 15 minutes before or 20 minutes after starting a meal. Intravenous injections may also be used for extreme hyperglycemia but must be performed under the supervision of a medical professional.
- Shortness of breath
- Sudden weight gain
- Swelling of your ankles or feet
- Low blood sugar (hypoglycemia)
- Serious allergic reactions
- Low potassium in your blood (hypokalemia)
- Heart failure