Rapamune

Rapamune is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection, and treat a rare lung disease called lymphangioleiomyomatosis. It has immunosuppressant functions in humans and is especially useful in preventing the rejection of kidney transplants. It inhibits the activation of T cells and B cells by reducing their sensitivity to interleukin-2 (IL-2) through mTOR inhibition.

Side effects:

• peripheral edema
• hypercholesterolemia
• abdominal pain
• headache
• nausea
• diarrhea
• pain
• constipation
• hypertriglyceridemia
• hypertension
• increased creatinine
• fever
• urinary tract infection
• anemia
• arthralgia
• thrombocytopenia